The study’s leaders believe that olanzapine may fill a need
The two groups received either 10 mg of olanzapine orally or matching placebo daily on days 1 through 4
Dosage forms: oral tablet (10 mg; 15 mg; 2
Introduction Chemotherapy-induced nausea and vomiting (CINV) can be a significant and distressing adverse event for patients undergoing cytotoxic cancer
Efficacy of Olanzapine 5 mg versus 10 mg for the Prophylaxis of Chemotherapy-Induced Nausea and Vomiting in Patients Receiving High Emetic Risk
Adults (≥18 years) with untreated, locally advanced, or metastatic gastric, hepatopancreaticobiliary (HPB), and lung cancers were randomly assigned
Children younger than 10 years of age—Use and dose must be determined by your doctor
Olanzapine belongs to a group of medicines called antipsychotics
You can find detailed information about this drug in the official Patient Information Leaflet (PIL)
Do not stop taking Chemotherapy-induced acute and delayed nausea or vomiting (high emetic risk [>90%]), prevention (off-label use): Oral: 5 or 10 mg on day of chemotherapy (day 1), followed by 5 or 10 mg once daily on days 2 to 4, in combination with antiemetics used for high emetic risk agents (Hashimoto 2020; Navari 2011; Navari 2016; Sutherland 2018)
The standard dosage of olanzapine for prophylaxis and treatment is 5 to 10 mg per day, with a maximum dose of 20 mg per day
Olanzapine (Zyprexa) can also be used to treat depression, in combination with fluoxetine (Prozac), when other treatments haven't worked well
Drowsiness (or sleepiness) is one of olanzapine’s most common side effects
Oral formulations: Common (1% to 10%): Chest pain, edema, hypertension, peripheral edema, postural/orthostatic hypotension, tachycardia
When used in the prevention of CINV, the dosage of olanzapine is usually 10 mg orally/daily, and it starts on the day of chemotherapy and lasts from day 2 to day 4
00, which is 97% off the average retail price of $178
We evaluated the efficacy of olanzapine 5 mg combined with standard antiemetic therapy for the prevention of chemotherapy-induced nausea and vomiting caused by cisplatin-based
seizures
Drowsiness, dizziness, lightheadedness, stomach upset, dry mouth, constipation, increased appetite, or weight gain may occur
, Symbyax), is recommended in patients predisposed to
You will be watched closely for at least 3 hours after you get this drug
It is also available as a disintegrating tablet in 5 Five infants aged 3 weeks to 6 months were breastfed during maternal olanzapine 2